A randomized, double-blind and placebo-controlled study of a Ganoderma lucidum polysaccharide extract in neurasthenia
Key Finding
Reishi mushroom supplementation improved subjective wellbeing, reduced fatigue, and enhanced vitality.
Plain-English Summary
This randomized, placebo-controlled trial examined the effects of Reishi mushroom (Ganoderma lucidum) supplementation in 26 adults over 12 weeks. Participants received 1440mg of Reishi extract daily or placebo.
While the primary focus was on cardiovascular markers, participants in the Reishi group reported significant improvements in subjective wellbeing, fatigue levels, and overall vitality. These effects align with Reishi's traditional use as an adaptogen.
Reishi contains polysaccharides and triterpenes that have immunomodulatory and anti-inflammatory properties. The mushroom has been used in traditional medicine for thousands of years to promote longevity and overall health. By reducing inflammation and supporting immune function, Reishi may indirectly support cognitive health and mental clarity. The supplement was very well-tolerated with no significant adverse events.