Randomised Controlled Trial

Mucuna pruriens reduces stress and improves the quality of semen in infertile men

Shukla KK, Mahdi AA, Ahmad MK, Shankhwar SN, Rajender S, Jaiswar SP - Evidence-Based Complementary and Alternative Medicine (2010) - Sample size: 60

Key Finding

Mucuna pruriens supplementation reduced stress, lowered cortisol, and increased dopamine levels over 3 months.

Plain-English Summary

This randomized controlled trial examined Mucuna pruriens supplementation in 60 men experiencing psychological stress and infertility. Participants received 5 grams of mucuna seed powder daily for 3 months.

The mucuna group showed significant improvements in stress markers, including reduced cortisol levels and improved sperm quality. Dopamine and adrenaline levels increased, while stress-related hormones decreased. Participants reported improved mood and reduced anxiety.

Mucuna pruriens is a natural source of L-DOPA, the direct precursor to dopamine. By increasing dopamine levels, mucuna supports motivation, mood, focus, and stress resilience. The herb has been used traditionally in Ayurvedic medicine for various neurological conditions. Beyond reproductive health, mucuna's dopaminergic effects may benefit cognitive function, mood disorders, and motivation. The supplement was well-tolerated throughout the study.

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